ISSN : 1301-5680
e-ISSN : 2149-8156
TURKISH JOURNAL OF
THORACIC AND
CARDIOVASCULAR SURGERY
Turkish Journal of Thoracic and Cardiovascular Surgery     
The relationship between deep venous thrombosis and undiagnosed malignant disease
Oral Hastaoğlu1, Onur Sokullu2, Soner Sanioğlu2, Şahin Şenay3, Koray Akkan1, Recep Er1, Fuat Bilgen2
1 Gümüşhane Devlet Hastanesi Kalp ve Damar Cerrahisi Kliniği, Gümüşhane
2 Dr. Siyami Ersek Göğüs Kalp ve Damar Cerrahisi Eğitim ve Araştırma Hastanesi Kalp ve Damar Cerrahisi Kliniği, İstanbul
3 Acıbadem Kadıköy Hastanesi Kalp ve Damar Cerrahisi Bölümü, İstanbul
Background: We investigated the relationship between deep venous thrombosis and undiagnosed malignant disease.

Methods: Forty-five consecutive patients (22 males, 23 females; mean age 59±18 years; range 19 to 83 years) in whom a diagnosis of deep venous thrombosis was made within a year were prospectively evaluated with respect to undiagnosed malignant disease. Evaluations included physical examination, routine laboratory tests, and abdominopelvic ultrasonography.

Results: Undiagnosed malignancy was detected in three patients (6.6%), namely, stomach, bladder, and lung cancers. Eighteen patients and 27 patients had idiopathic and secondary deep venous thrombosis, respectively. Malignant disease was found in two patients (11.1%) in the idiopathic group, and in one patient (3.7%) in the secondary group.

Conclusion: An undiagnosed malignancy may be the underlying cause of deep venous thrombosis, particularly in idiopathic cases. Early diagnosis of a malignant disease would be beneficial to the patients and the healthcare centers.

Keywords : Neoplasms, unknown primary/diagnosis; venous thrombosis/ complications
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