An evaluation of 6% hydroxyethyl starch 130/0.4 use in fluid therapy following coronary artery surgery

Ahmet Barış Durukan,

doi:10.5606/tgkdc.dergisi.2013.7256

Ahmet Barış Durukan¹, Hasan Alper Gürbüz¹, Elif Durukan², Nevriye Salman³, Murat Tavlaşoğlu⁴, Fatih Tanzer Serter¹, Halil İbrahim Uçar¹, Cem Yorgancıoğlu¹

¹Department of Cardiovascular Surgery, Medicana International Ankara Hospital, Ankara, Turkey
²Department of Public Health, Medicine Faculty of Başkent University, Ankara, Turkey
³Department of Anesthesiology and Reanimation, Medicana International Ankara Hospital, Ankara, Turkey
⁴Department of Cardiovascular Surgery, Diyarbakır Military Hospital, Diyarbakır, Turkey

DOI : 10.5606/tgkdc.dergisi.2013.7256

Background: This study aims to compare the effects of 6% hydroxyethylstarch 130/0.4 with a commonly used balanced electrolyte solution in patients undergoing coronary artery bypass surgery.

Methods: One hundred and fifty seven patients who underwent coronary artery bypass surgery were randomized into two groups. The first group received 6% hydroxyethyl starch 130/0.4, while the second group received a commonly used balanced electrolyte solution. The effects of both solutions on postoperative outcomes were studied.

Results: Six percent hydroxyethyl starch 130/0.4 did not increase postoperative blood loss and the amount of blood and blood products (p>0.05). No adverse effect was observed on renal and pulmonary functions. Intubation time, intensive care unit stay and postoperative duration of hospital stay did not differ between the groups (p>0.05). Hydroxyethyl starch had no effect on the occurrence of postoperative atrial fibrillation (p>0.05).

Conclusion: Six percent hyroxyethyl starch 130/0.4 may be considered safe in fluid therapy following coronary bypass surgery.

Keywords : Cardiac surgery; crystalloid solutions; hydroxyethyl starch

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