ISSN : 1301-5680
e-ISSN : 2149-8156
TURKISH JOURNAL OF
THORACIC AND
CARDIOVASCULAR SURGERY
Turkish Journal of Thoracic and Cardiovascular Surgery     
Demographical data and outcomes of surgically treated patients with the diagnosis of infective endocarditis: a multi-center retrospective study
Mustafa Oylumlu1, Mehmet Ali Elbey1, Emin Kalkan2, Serkan Akdağ3, Kerem Özbek4, Nihan Kahya Eren5, Selim Topçu6, Fatih Kahraman7, Mahmut Akpek8, Sinan Demirtaş9, Abdulkadir Yıldız1, Mesut Aydın1, Murat Yüksel1
1Dicle Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Diyarbakır, Türkiye
2Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye
3Yüzüncü Yıl Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Van, Türkiye
4Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Tokat, Türkiye
5İzmir Atatürk Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, İzmir, Türkiye
6Atatürk Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Erzurum, Türkiye
7Süleyman Demirel Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Isparta, Türkiye
8Erciyes Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Kayseri, Türkiye
9Dicle Üniversitesi Tıp Fakültesi, Kalp ve Damar Cerrahisi Anabilim Dalı, Diyarbakır, Türkiye
DOI : 10.5606/tgkdc.dergisi.2014.8386
Background: This study aims to investigate the demographic and clinical characteristics and echocardiographic and microbiological findings of the patients as well as the outcomes of surgery undergoing surgical treatment with the diagnosis of infective endocarditis in Turkey.

Methods: Between January 2005 and August 2012 116 patients (65 males, 51 females; mean age 43±16 years; range 14 to 80 years) with the diagnosis of infective endocarditis who underwent surgery in 13 tertiary university/research and education hospitals were included in this multi-center study. Demographic and clinical characteristics of the patients, and echocardiographic and microbiological findings, surgical indications and outcomes of surgery were retrospectively analyzed.

Results: The most common symptom on admission and physical finding was fever. Blood cultures were negative in 35 patients (30%). Staphylococci were the most common microbiological pathogens (22%). Congestive heart failure was the most common indication for surgery in 56 patients (48%). Valve repair was performed in 12 patients (10%), valve replacement was the procedure of choice in 104 patients (90%). Thirty-three patients undergoing surgical treatment died in the postoperative period. The mortality rate was 28%. Independent predictors of surgical mortality were Class 3-4 functional capacity, elevated C-reactive protein, and renal dysfunction.

Conclusion: Although complicated cases of infective endocarditis can be treated through surgery, surgical morbidity and mortality is still high.

Keywords : Epidemiology; infective endocarditis; surgical treatment
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