ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Results of surgical resection in the treatment of small-cell lung cancer
Ülkü Yazıcı1, Ertan Aydın1, İrfan Taştepe1, Erkmen Gülhan1, Pınar Yaran2, Nurettin Karaoğlanoğlu1, Yetkin Agaçkıran1, Sadi Kaya1
1Department of Thoracic Surgery, Atatürk Chest Diseases and Thoracic Surgery, Training and Research Hospital, Ankara
2Department of Thoracic Surgery, Special Akay Hospital, Ankara
DOI : 10.5606/tgkdc.dergisi.2011.093
Background: This study aims to investigate the role of a surgical approach in the treatment of small-cell lung cancer (SCLC), and evaluate the possible effects of combining the surgical approach with other treatment modalities for survival.

Methods: Twenty patients (16 males, 4 females; mean age 58.3 years; range 41 to 76 years) who had a clinical and radiological suspicion of malignancy, who underwent an exploratory thoracotomy since diagnostic methods proved ineffective, and whose pathological results were reported as SCLC between January 1998 and January 2008 were reviewed retrospectively. Ten upper lobectomies, two lower lobectomies, six pneumonectomies and two inferior bilobectomies were performed along with radical lymph node dissection. All cases were evaluated according to age, gender, diagnostic methods, the operations performed, postoperative follow-up and survival results.

Results: The results of the postoperative histopathological assessments were reported as small-cell lung cancer and mixed type tumors were observed in 11 cases. Five of the cases were stage 1, six were stage 2, and nine were stage 3. During the postoperative period all cases received chemotherapy, and radiotherapy was applied to the cases with nodal metastases. The five-year survival rate was calculated as 76% for stage 1 and 2 cases, 13% for stage 3 cases and 86% and 15% for N0 and N1-2 cases, respectively.

Conclusion: Surgical treatment for SCLC can be considered in early stage (T1-2 N0) cases. In the presence of N2, a surgical approach should be avoided. Postoperative chemotherapy should be applied after surgical resection, and mediastinal radiotherapy should be added in cases with nodal metastasis.

Keywords : Lung cancer; lymph node dissection; small cell lung cancer; surgical
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