ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
The results of coronary artery surgery in women and men under the age of 45
Mehmet Kaya1, Taner İyigün1, Müzeyyen İyigün2, İhsan Bakır1, Mehmet Yeniterzi1
1Mehmet Akif Ersoy Göğüs Kalp Damar Cerrahi Eğitim ve Araştırma Hastanesi, Kalp ve Damar Cerrahi Kliniği, İstanbul, Türkiye
2Mehmet Akif Ersoy Göğüs Kalp Damar Cerrahi Eğitim ve Araştırma Hastanesi, Anestezi ve Reanimasyon Kliniği, İstanbul, Türkiye
DOI : 10.5606/tgkdc.dergisi.2013.7564
Background: This study aims to investigate possible risk factors with the morbidity and mortality rates in women and men under the age of 45 undergoing coronary artery bypass graft (CABG) surgery.

Methods: Between August 2009 and May 2012, a total of 230 patients (189 males, mean age 41.4±3.4 years; range 35 to 45 years; 41 females, mean age 41.9±3.0; range 32 to 45 years) under the age of 45 who underwent CABG in our clinic were included. Patients were divided into two groups according to their gender and a comparative analysis was performed.

Results: The mean age was 41.9 years (range, 32 to 45 years) in women and 41.4 years (range, 35 to 45 years) in men. Unstable angina pectoris (p<0.001), hypertension (p<0.001), dyslipidemia (p=0.009) ischemic mitral regurgitation (p=0.03), mitral valve annuloplasty (p=0.03), postoperative atrial fibrillation, (p=0.031) and wound infections (p<0.001) were statistically significant with female gender. Syntax score (p<0.001), smoking (p=0.002), chronic obstructive pulmonary disease (p<0.001), number of distal anastomoses (p<0.001), ejection fraction (p<0.001) were statistically significant associated with male gender. In-hospital mortality rates were similar in men and women. There was no significant difference in the early- and midterm survival rates of female and male patients following surgery. The mean postoperative follow-up was 18.2±9.5 months in women and 31.6±19.3 months in men.

Conclusion: Our study results suggest that the incidence of traditional risk factors including dyslipidemia and hypertension is higher in women.

Keywords : Coronary artery bypass graft surgery; coronary artery disease; young and middle age
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