An evaluation of renal functions in pulsatile and non-pulsatile cardiopulmonary bypass in the elderly

Faruk Hökenek,

doi:10.5606/tgkdc.dergisi.2013.7164

Faruk Hökenek¹, Mete Gürsoy², Vedat Bakuy², Ali Aycan Kavala², Tarık Demir¹, Füsun Gülcan¹, Barbaros Kınoğlu¹

¹Department of Cardiovascular Surgery, Medical Park Bahçelievler Hospital, İstanbul, Turkey
²Department of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey

DOI : 10.5606/tgkdc.dergisi.2013.7164

Background: This study aims to evaluate the effects of pulsatile and non-pulsatile cardiopulmonary bypass techniques on renal functions in elderly.

Methods: Between January 2011 and June 2011, 41 patients aged above 70 years who underwent coronary artery bypass grafting (CABG) in our clinic were enrolled in the study. Patients were randomly divided into two groups according to the perfusion technique: pulsatile and non-pulsatile flow. Preoperative, post-cardiopulmonary bypass and at third day following surgery, creatinine, cystatin C, blood urea nitrogen values, urine output during cardiopulmonary bypass and the incidence of acute kidney injury were recorded.

Results: At third day following operation, cystatin C, creatinine and blood urea nitrogen values were significantly lower in pulsatile flow group. A significant difference was observed between the groups in terms of urine output during cardiopulmonary bypass and the incidence of acute kidney injury.

Conclusion: Pulsatile flow cardiopulmonary bypass is a simple and safe method which may prevent acute kidney injury in elderly.

Keywords : Acute kidney injury; cystatin C; non-pulsatile flow; pulsatile flow

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