ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Thymic carcinoid with multiple endocrine neoplasia type 1: a case report
Ertan Aydın1, Ülkü Yazıcı1, Yetkin Ağaçkıran2, Ali Çelik1, Nurettin Karaoğlanoğlu1
1Department of Thoracic Surgery, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey
2Department of Pathology, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey
DOI : 10.5606/tgkdc.dergisi.2013.5031
Thymic carcinoid is a rare neuroendocrine tumor of the thymus. Apart from sporadic cases, it is usually associated with multiple endocrine neoplasia type 1 (MEN1). Thoracic computed tomography (CT) revealed an anterior mediastinal mass with a size of 10 cm in diameter, encroaching into the left thoracic cavity in a 39-year-old male case with MEN1- related giant thymic carcinoid who was admitted due to chest pain. A computed tomography-guided percutaneous tru-cut biopsy demonstrated a carcinoid tumor of the thymus. Tumor was resected through left thoracotomy. Pathologic analyses of the specimen revealed thymic carcinoid tumor, mostly encapsulated with local pericardial tissue invasion. The patient with familial MEN1 was asymptomatic for the past seven months. Thymic carcinoid is the leading cause of death in patients with MEN1 disease. Early diagnosis and treatment of this condition would help to minimize morbidity and mortality rate.
Keywords : Multiple endocrine neoplasia; surgery; thymic carcinoid
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