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10.5606/tgkdc.dergisi.2015.10700
Mycobacterial infections in heart transplant recipients
Department of Cardiothoracic Surgery, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, China
DOI : 10.5606/tgkdc.dergisi.2015.10700
Mycobacterial infections frequently develop as a
consequence of immunosuppression and are often a
causative cause of morbidity and mortality. Epidemiology
and clinical characteristics of mycobacterial infections
after solid organ and stem cell transplantation have been
well-described. However, due to the rarity of clinical data,
the pertinent aspects of mycobacterial infection after heart
transplantation remain to be clarified. A comprehensive
literature collection revealed mycobacterial infections
after heart transplantation usually developed late after
transplantation. Cutaneous and pulmonary infections
were the most common with Mycobacteria tuberculosis
being the prevailing pathogen. Unlike in solid organ
transplant recipients, non-tuberculous mycobacterial
infections in heart transplant recipients were sporadic
with no prevailing species. Combined drug therapy
seemed to be more effective than monotherapy. The
overall survival rate was 84.2%.
Keywords : Heart transplantation; microbiology; mycobacterium
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