A very rare side effect of amlodipine: non-cardiogenic pulmonary edema

Kemal Kiraz; Mustafa Çörtük; Alaa Quisi; Selahattin Akyol; Ömer Poyraz

doi:10.5606/tgkdc.dergisi.2017.13507

Kemal Kiraz¹, Mustafa Çörtük², Alaa Quisi³, Selahattin Akyol³, Ömer Poyraz⁴

¹Departments of Chest Diseases, Antalya Atatürk State Hospital, Antalya, Turkey
²Department of Chest Diseases, Medical Faculty of Karabük University, Karabük, Turkey
³Department of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey
⁴Departments of Internal Medicine, Antalya Atatürk State Hospital, Antalya, Turkey

DOI : 10.5606/tgkdc.dergisi.2017.13507

Calcium channel blockers are among the most widely used drugs in cardiovascular medicine. Amlodipine, which is both cost-effective and taken once daily, is one of the most commonly prescribed agents. Although peripheral edema is a well-known side effect of amlodipine, non-cardiogenic pulmonary edema associated with amlodipine is very rare. Herein, we describe a 24-year-old female case of non-cardiogenic pulmonary edema after ingestion of 300 milligram of amlodipine orally for a suicide attempt. The patient was successfully treated with fluid replacement, inotropic drugs, and mechanically ventilation. To the best of our knowledge, this is the first case reported in Turkey.

Keywords : Amlodipine; drug overdose; pulmonary edema; suicide attempt

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