Antibiotic Administration in High Infection Risk Patients After Cardiac Surgery

Hakan GERÇEKOĞLU, Hasan KARABULUT, Ahmet KORUKÇU, Murat DEMİRTAŞ, Tufan ŞENER, Yıldırım CÖMERTOĞLU, Onur SOKULLU, Hüseyin TOKLU, Besim YİĞİTER

Siyami Ersek Göğüs Kalp ve Damar Cerrahisi Merkezi. Kalp ve Damar Cerrahisi Bölümü

In our center, between February 1993 - November 1997, 1220 heart operations were performed by the same surgical team. Twenty-six of these patients whose sternum had been left open due to myocardial edema, intraoperative bleeding, Iow cardiac output, ventricular arrhythmias, raised EEP (End Expiratory Pressure) and applied postoperative internal resuscitation have been examined. Cefazolin were administered to the patients in group I (n=12) and Vancomycin in group II (n=14).

Totally 232 culture has been taken in order to follow the improvement of infection. (blood n=39, intra- muscular catheter n=46, tracheal secretion n=27, mediasten n =86, wound n =24).

Four of 26 patients were lost in the postoperative period, two of them was lost due to low cardiac output and the another from the multiorgan failure due to sepsis.

There was no positive cultur of mediasten in group II (p<0.008) less positive cultur have been indicated in respect of wound in group II (p<0.05), Group II seems to have a berter prognosis in respect of infection and hospitalisation period.

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