- Home
- Articles
-
10.5606/tgkdc.dergisi.2024.25806
Lung transplantation in children
Jonas Peter Ehrsam1,2,3, Olga Meier Adamenko3, Manjinder Pannu4, Othmar Markus Schöb1,2,3, Ilhan Inci1,2,3,4
1School of Medicine, University of Zurich, Zurich, Switzerland
2Department of Thoracic Surgery, Klinik Hirslanden Zurich, Zurich, Switzerland
3Klinik Hirslanden Zurich, Centre for Surgery, Zurich, Switzerland
4University of Nicosia Medical School, Nicosia, Cyprus
DOI : 10.5606/tgkdc.dergisi.2024.25806
Lung transplantation is a well-established treatment for
children facing advanced lung disease and pulmonary vascular
disorders. However, organ shortage remains highest in
children. For fitting the small chest of children, transplantation
of downsized adult lungs, lobes, or even segments were
successfully established. The worldwide median survival after
pediatric lung transplantation is currently 5.7 years, while
under consideration of age, underlying disease, and peri- and
posttransplant center experience, median survival of more than
10 years is reported. Timing of referral for transplantation,
ischemia-reperfusion injury, primary graft dysfunction, and
acute and chronic rejection after transplantation remain the
main challenges.
Keywords : Children, lung donor, lung transplantation, pediatrics
Viewed : 829
Downloaded : 240