ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Lung transplantation in children
Jonas Peter Ehrsam1,2,3, Olga Meier Adamenko3, Manjinder Pannu4, Othmar Markus Schöb1,2,3, Ilhan Inci1,2,3,4
1School of Medicine, University of Zurich, Zurich, Switzerland
2Department of Thoracic Surgery, Klinik Hirslanden Zurich, Zurich, Switzerland
3Klinik Hirslanden Zurich, Centre for Surgery, Zurich, Switzerland
4University of Nicosia Medical School, Nicosia, Cyprus
DOI : 10.5606/tgkdc.dergisi.2024.25806
Lung transplantation is a well-established treatment for children facing advanced lung disease and pulmonary vascular disorders. However, organ shortage remains highest in children. For fitting the small chest of children, transplantation of downsized adult lungs, lobes, or even segments were successfully established. The worldwide median survival after pediatric lung transplantation is currently 5.7 years, while under consideration of age, underlying disease, and peri- and posttransplant center experience, median survival of more than 10 years is reported. Timing of referral for transplantation, ischemia-reperfusion injury, primary graft dysfunction, and acute and chronic rejection after transplantation remain the main challenges.
Keywords : Children, lung donor, lung transplantation, pediatrics
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