ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Changes of the Erythrocyte Membrane Adenosine- 5’Triphosphatase Activities in the Prosthetic Heart Valve Replaced Patients at Postoperative Period and Interrelations of These Changes with Hemolysis
Orhan Kemal SALİH, Şekip Kazım ÇELİK, Mustafa Kemal OSKAY, Lülüfer TAMER
Çukurova Üniversitesi Tıp Fakültesi Göğüs Kalp Damar Cerrahisi ve Biyokimya Anabilim Dalı, SSK Mersin Hastanesi Göğüs Kalp Damar Cerrahisi

In this study erythrocyte membrane ATPase enzyme activity changes and hemolysis developed in the postoperative period after replacement of the same type of prosthetic heart valves were investigated in twenty patients. The findings were compared with the values obtained from ten healthy people. Hemolysis was not observed in the preoperative period of the patient group; but mild degree of hemolysis was detected in the fourth and the eighth months of the postoperative period. Although no hemolysis occured in the patient group at the preoperative period, a significant decrease was observed in each of three ATPase enzyme activities as compared to the control group. At the fourth and the eighth months of postoperative period, there were significant decreases in the ATPase enzyme activities with mild hemolysis when compared to preoperative period. These results indicated that the ATPase enzyme activities decreased in the patient group could not be directly related with hemolysis and some other factors might contribute to the loss enzyme activities.

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