e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
All arterial versus non-total arterial coronary artery bypass grafting in diabetic patients: A systematic review and meta-analysis
Erina Febriani Widiastari1, Wirya Ayu Graha2,4, Harry Raihan Alzikri1, Nurima Ulya Dwita3,4, Marolop Pardede3,4
1Undergraduate Medical Study Program, Faculty of Medicine, YARSI University, Jakarta, Indonesia
2Division of Adult Cardiac Surgery, Harapan Kita National Cardiovascular Center Hospital, Jakarta, Indonesia
3Department of Thoracic and Cardiovascular Surgery, RSUD Dr. Chasbullah Abdulmadjid Kota Bekasi, Indonesia
4Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
DOI : 10.5606/tgkdc.dergisi.2025.27636
Background: In this meta-analysis, we compare total arterial revascularization versus non-total arterial revascularization coronary artery bypass grafting in diabetic patients and discuss long-term survival rate and early mortality rate, cerebrovascular accident, myocardial infarction, sternal wound infection.

Methods: We searched the Cochrane Library, PubMed, Thieme-Connect and Sage Pub databases for studies which were published from January 2003 to October 2023. Observational studies with propensity-score matched analysis comparing total arterial revascularization versus non-total arterial revascularization coronary artery bypass grafting in diabetic patients were included. The risk of bias was analyzed. Fixed-effects model and random-effects meta-analysis with leave-one-out method as sensitivity analysis were performed.

Results: Six observational studies which were published involving a total of 15,336 patients were included in the meta-analysis. There were significant differences in the long-term survival rates and early myocardial infarction. Total arterial revascularization had higher survival rate (incidence rate ratio [IRR]=0.85, 95% confidence interval [CI]: 0.74-0.98, p=0.02) and lower myocardial infarction event than non-total arterial revascularization (odds ratio [OR]=0.45, 95% CI: 0.22-0.92, p=0.03).

Conclusion: Total arterial revascularization is significantly associated with higher survival rate and lower early myocardial infarction than non-total arterial revascularization in diabetic patients undergoing coronary artery bypass grafting.

Keywords : Arterial grafting, coronary artery bypass grafting, diabetes mellitus, meta-analysis, survival rate
Viewed : 2
Downloaded : 3