Comparison of Effccts of The Roller and The Centrifugal Pump on The Immune System

Mehmet Salih BİLAL, Osman BAYINDIR, Selim ERENTÜRK, Bekir KOCAZEYBEK, Özdem ANG, Işık YALÇIN, Aydın AYTAÇ, Cem'i DEMİROĞLU

İstanbul Üniversitesi Kardiyoloji Enstitüsü, İstanbul

We plannet this study to evaluate how the centrifugal pump effect on the immune system compares with the roller pump. A Contrifugal pump was used in 10 patients with ischemic heart disease and a roller pump in another 10. Leucocyte count, leucocyte formula, opconication, NBT reduction test, bactrericidal test and complement level (C3 and C4) wcre measured to show the changes in the non-specific immune system. Changes in immunoglobulins (IgG, IgM and IgA) were determined for humoral immuniry and E-rozette and EAC-rozette for cellular immunity. We observed some disturbances in the immune system of all the patients during and after cardiopulmonary bypass. As a result, we couldn't determine any difference concerning non-specific, humoral and cellular immunity in the two groups. New methods preventing immunosupression are necessary and this is an important subject in the future of open heart surgery.

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