Two-dimensional echocardiograph is considered to be the most effetive method for detecting vegetations in infective endocarditis. Futhermore, it shows the complications of infective endocarditis. Futhermore, it shows the complications of infective endocarditis. Futhetmore, it shows the complications of infective endocarditis (perivalvar abscess, ruptured chordae tendineae, mycotic aneurysm, intracardiac fistula paraprosthetic regugitation). 34 patients with infective endocarditis (IE) had trans-thoracic echocardiography (TTE) to investigate the relation between the presence, size, response to treatment of echocardiographic vegetation and the complication rate in IE. Eight of these also had tronsoesopageal echocardiography (TOE). Nine patients were female, 25 male. 17 patients had prosthetic valves. The mean follow-up time was 44 days. Perivalvar abscess, death, congestive heart failure, emboli were more common in patents with echocardiographic vegetation, vegatation larger than 10 mm, without decreasing vegetation size during treatment. Surgical treatment was more commonly required in patient without vegatation and with decreasing vegatation size during treament.