ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
OPEN HEART SURGERY IN PATIENTS WITH LOW-GRADE SMALL LYMPHOCYTIC MALIGNANCY
Abdullah Kemal Tuygun, Nurgül Yurtseven, Süheyla Keser, Pelin Karaca, Aybanu Tuygun, Adlan Olsun, Sabri Dağsalı
Siyami Ersek Göğüs Kalp Damar Cerrahisi Eğitim ve Araştırma Hastanesi, Kalp Damar Cerrahisi Kliniği, İstanbul
Background:The unknown but presumably reduced life expectancy of patients with malignant neoplasms may dissuade surgeons from performing necessity coronary and valvular heart operations. Low-grade small lymphocytic malignancies (encompassing chronic lymphocytic leukemia and some types of non-Hodgkin lymphoma) are seen in elderly patients. Open cardiac procedures are known to have increased risk of postoperative infection and other morbidities in these immunodeficient patients.

Methods: Between June 1999 - January 2002 five patients (aged 49-72 years; 1 woman, 4 men) with these lymphocytopathologic diseases (2 with chronic lymphocytic leukemia and 3 with non-Hodgkin lymphoma) underwent cardiac operations. One patient underwent mitral valve replacemant and four patients underwent coronary artery bypass grafting.

Results: There was no operative death and morbidity. Average stay in hospital was 8 days. During the follow-up to 12 months, 1 patient with chronic lymphocytic leukemia underwent chemoteraphy. Cardiac and lymphocytopathologic status remained stable in others.

Conclutions: Patients with low-grade small lymphotic malignancies can undergo cardiac surgery under extracorporeal circulation with acceptable mortality but with possible increased risk of postoperative infection. If a cardiac operation is planned to a patient with low grade lymphocytic leukemia, an additional prrocedure or approach would not be required than other patients who will be undergone cardiac surgery.

Keywords : Lymphoprolipherative, open heart surgery, lymphoma, leukemia,
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