ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Recurrent deep vein thrombosis in a 11-year-old girl with hereditary protein-C deficiency
Mustafa Göz, Ömer Çakır, Nesimi Eren
Dicle Üniversitesi Tıp Fakültesi, Kalp ve Damar Cerrahisi Anabilim Dalı, Diyarbakır
Protein-C is a plasma protein, which plays an important role in the physiologic anticoagulan system. In its hereditary insufficiencies, venous and arterial thromboses occur. An 11-year-old girl presented with pain, edema and movement restriction of the left leg, we learned these occured four days after a febrile upper respiratory tract infection. It was pointed out that she had oedema on the same leg but received no treatment while being hospitalized and treated due to a febrile attack when she was 1-year-old. In physical examination there were 3 cm differences between two lower extremities in diameter. Homans test was positive. In Doppler USG there were distally chronical and proximally acute deep vein thrombosis. In family search familial protein- C insufficiency was found. Subcutaneus heparin and oral anticoagulan were initiated. There were no recurrences during six month-oral thromboemboli profilacty period.
Keywords : Venous thromboembolism; pediatric; protein-C deficiency
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