A 78-year-old female was admitted to our clinic
with shortness of breath and fatigue. Her physical
examination revealed the signs of decompensated heart
failure. She underwent primary percutaneous coronary
intervention (PCI) to the left anterior descending artery
due to a history of acute anterior myocardial infarction
(MI) three weeks ago. Transthoracic echocardiography
(TTE) showed a dilated left ventricle (LV) with
severely reduced systolic function with an apical
thrombus diameter with 1.6¥2.1 cm (Figure
1a).
Based on the clinical signs and TTE findings, the
diagnosis of decompensated systolic heart failure
was made and standard heart failure therapy was
started. Approximately eight hours later, the patient
became symptomatic about bilateral lower limb pain,
paralysis, and low back pain and she developed severe
acute respiratory distress with oxygen desaturation
to mid-70s on room air. Her femoral pulses were
both non-palpable, the bilateral lower extremities
were cold, and the left foot was cyanotic. Doppler
ultrasound was unable to detect any pulse at the
bilateral common femoral arteries, and the abdominal
contrasted computed tomography (CT) which was
subsequently conducted revealed a huge thrombus at
the distal abdominal aorta (Figure
1b). Her respiratory
status declined requiring intensive care unit admission,
despite 15 L non-rebreather mask, and the patient had
intubation and mechanical ventilation. After discussion
with our cardiac surgeons, we decided to treat the patient with endovascular approach to restore the
antegrade flow to the distal vessels quickly. A 7-F
introducer was inserted into the left brachial artery.
Diagnostic angiography showed a large thrombus in
the distal abdominal aorta without renal and mesenteric arterial involvement (Figure
1c). After administration
of local tissue plasminogen activator (t-PA) to the
thrombus site, we decided to maintain the procedure
with stenting due to insufficient distal flow. After
wiring the right and left common iliac artery (CIA)
with 0.035-inch angled Glidewires (Terumo Medical
Corp.,, Somerset, NJ, USA), two peripheral selfexpandable
stents (7¥80 mm and 8¥80 mm Polaris-pp,
Qualimed innovative Germany) were placed to the
aortic bifurcation simultaneously. We were unable to
perform the final kissing balloon inflation due to the
possibility of distal embolization of the thrombus which
was compressed between the two stents. Repeated
angiography showed normal flow patency of both right
and left CIA (Figure
1d). The patient was extubated
on the first day after the endovascular procedure and
discharged with warfarin 5 mg on the fifth day of
hospitalization without any complications.
Figure 1: (a) A Transthoracic echocardiography appearance
of the left ventricle apical thrombus. (b) Contrast-enhanced
computed tomography of the distal aorta showing luminal filling
defect within the aortoiliac bifurcation. (c) An angiographic
image in an anteroposterior view showing the totally occluded
and left common iliac artery and subtotally occluded right
common iliac artery with the thrombus. (d) Final angiogram with
satisfactory outcomes.
Acute aortic occlusion is a catastrophic condition
with high morbidity and mortality rates and often
the most challenging vascular pathology to treat
which requires an urgent therapeutic intervention.[1]
Endovascular treatment strategy can be used to restore
the antegrade flow to the distal vessels quickly,
relieve symptoms, and further prevent loss of territory limb.[2,3] Although open surgery, embolectomy, and
thrombolytic infusion are other alternatives, these
group patients usually have a lot of comorbidities and
high risk for general anesthesia and surgery as well as
bleeding complications. Percutaneous intervention can
be used in the treatment of such patients as a bail-out
procedure.
Declaration of conflicting interests
The authors declared no conflicts of interest with respect to
the authorship and/or publication of this article.
Funding
The authors received no financial support for the research
and/or authorship of this article.