Ex vivo lung perfusion in lung transplantation: a case report

Ali Yeginsu; Merih Kalamanoğlu Balcı; Mustafa Vayvada; Atakan Erkılınç; Cemal Asım Kutlu

doi:10.5606/tgkdc.dergisi.2016.11111

Ali Yeginsu¹, Merih Kalamanoğlu Balcı², Mustafa Vayvada¹, Atakan Erkılınç³, Cemal Asım Kutlu¹

¹Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Göğüs Cerrahisi ve Akciğer Nakli Kliniği, İstanbul, Türkiye
²Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, İstanbul, Türkiye
³Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Anestezi ve Reanimasyon Kliniği, İstanbul, Türkiye

DOI : 10.5606/tgkdc.dergisi.2016.11111

Ex vivo l ung p erfusion i s a m ethod p erformed f or improving functions of donor lungs which are in unusable condition. Criteria which were initially good in a 29-year-old donor deteriorated in time. Partial pressure of oxygen in arterial blood decreased from 310 mmHg to 230 mmHg. We decided to perform ex vivo lung perfusion before lung transplantation. Condition of lungs improved significantly with 210 minutes of ex vivo lung perfusion and partial oxygen pressure increased to 485 mmHg. Subsequently, we transplanted the lungs to a 56-year-old male receiver suffering from severe chronic obstructive lung disease.

Keywords : Donor; ex vivo lung perfusion; lung transplantation

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