Ahmet Kürşat Bozkurt1, Hakkı Tankut Akay2, İsmet Tanzer Çalkavur3, Mustafa Şırlak4, Ozan Onur Balkanay1, Emrah Uğuz5, Suat Doğancı6, Adil Polat7, Serdar Bayrak8, Şahin Bozok9, Ahmet Barış Durukan10, Nevzat Erdil11, Dilek Erer12, Şahin Şenay13, Ertekin Utku Ünal14, Soner Yavaş5
1Department of Cardiovascular Surgery, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
2Department of Cardiovascular Surgery, Başkent University, Faculty of Medicine, Ankara, Turkey
3Department of Cardiovascular Surgery, Ege University, Faculty of Medicine, Izmir, Turkey
4Department of Cardiovascular Surgery, Ankara University, Faculty of Medicine, Ankara, Turkey
5Department of Cardiovascular Surgery, Health Sciences University, Ankara City Hospital, Ankara, Turkey
6Department of Cardiovascular Surgery, Health Sciences University, Gülhane Faculty of Medicine, Ankara, Turkey
7Department of Cardiovascular Surgery, Health Sciences University, Bağcılar Training and Research Hospital, Istanbul, Turkey
8Department of Cardiovascular Surgery, Dokuz Eylül University, Faculty of Medicine, Izmir, Turkey
9Department of Cardiovascular Surgery, Izmir Bakırçay University, Faculty of Medicine, Izmir, Turkey
10Department of Cardiovascular Surgery, MediGüneş Salihli Private Hospital, Manisa, Turkey
11Department of Cardiovascular Surgery, Inönü University, Turgut Özal Medical Center, Malatya, Turkey
12Department of Cardiovascular Surgery, Gazi University, Faculty of Medicine, Ankara, Turkey
13Department of Cardiovascular Surgery, Acıbadem University, Faculty of Medicine, Istanbul, Turkey
14Department of Cardiovascular Surgery, Hitit University, Faculty of Medicine, Çorum, Turkey
These evidence-based guidelines from the Turkish Society of Cardiovascular
Surgery, National Society of Vascular and Endovascular Surgery, and Phlebology
Society intend to support clinicians in best decisions regarding the treatment
of venous thromboembolism (VTE). The Editor was selected by the three
national societies and was tasked with the recruitment of the recognized panel.
All financial support was solely derived from the sponsoring societies without
the direct involvement of industry or other external stakeholders. The panel
prioritized clinical questions and outcomes according to their importance for
clinicians in terms of VTE. The panel agreed on 42 recommendations under
15 headings for the diagnosis, initial management, secondary prevention of VTE,
and treatment of recurrent VTE events. Important recommendations included the
use of ultrasonography, preference for home treatment over hospital treatment
for uncomplicated VTE, preference for direct oral anticoagulants (DOACs) over
vitamin K antagonists for primary treatment of cancer and non-cancer-related
VTE, extended or indefinite anticoagulation with DOACs in selected high-risk
patients. Early catheter-directed thrombectomy was recommended in only young
symptomatic patients with a diagnosis of fresh iliofemoral deep vein thrombosis.
Keywords : Anticoagulant therapy, cancer-related venous thromboembolism, catheter-directed thrombectomy, deep vein thrombosis, direct oral anticoagulants, evidence-based medicine, post-thrombotic syndrome, practice guideline, venous thromboembolism
