ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Neurocognitive effects of cardiopulmonary bypass in coronary artery bypass surgery
İhsan İşkesen, Funda Yıldırım, Hayrettin Şirin
Celal Bayar Üniversitesi Tıp Fakültesi Kalp ve Damar Cerrahisi Anabilim Dalı, Manisa
Background: We evaluated the effect of cardiopulmonary bypass on neurocognitive functions in patients undergoing coronary bypass surgery.

Methods: This prospective study included 36 patients (24 women, 12 men; mean age 57±2 years) who underwent coronary artery bypass surgery. The patients were administered a neurocognitive test battery before and one month after surgery, including the Health-Related Quality of Life (SF-36), Standardized Mini-Mental State Examination, Hamilton Anxiety Scale, Pittsburgh Sleep Quality Index, and Epworth Sleepiness Scale. In addition, demographic data and hemodynamic parameters of the patients were evaluated.

Results: Compared to the preoperative scores, significant improvements were found in the psychologic and motor or physical function subsets of the SF-36 and Hamilton Anxiety Scale after the operation (p<0.05). Scores of the Standardized Mini-Mental State Examination remained unchanged (p>0.05). There was a decrease in the Pittsburgh Sleep Quality Index and an increase in the Epworth Sleepiness Scale, but both did not reach a significant level.

Conclusion: Coronary bypass surgery improves the patients’ quality of life, but it significantly decreases motor and psychologic parameters. Decrease in cognitive functions is not significant.

Keywords : Cardiopulmonary bypass/psychology; cognition disorders/etiology; neuropsychological tests; postoperative complications; quality of life; questionnaires
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