ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
The role of standard and extended cervical mediastinoscopy in the staging of non-small cell lung cancer patients
İlker İskender1, Çağatay Tezel2, Salih Zeki Kadıoğlu2, Altan Kır2
1Department of Thoracic Surgery, Dr. Selahattin Cizrelioğlu Cizre State Hospital, Şırnak
2Department of Thoracic Surgery, Süreyyapaşa Chest Diseases and Thoracic Surgery Hospital, İstanbul
DOI : 10.5606/tgkdc.dergisi.2011.052
Background: In this study, our experience with standard cervical mediastinoscopy (SCM) and extended cervical mediastinoscopy (ECM)-performed for preoperative staging of non-small cell lung cancer (NSCLC) is presented.

Methods: Two hundred and eight consecutive patients with the diagnosis or prediagnosis of NSCLC admitted to our clinic between September 2005 and December 2007 were evaluated. Twelve patients were excluded from the study due to neoadjuvant treatment (n=7) and abnormal morphology preventing proper mediastinoscopy (n=5). Standard cervical mediastinoscopy was performed in all patients and concurrent ECM and SCM in 47 patients who had a tumor in the left lung. We performed thoracotomies in patients with a negative mediastinoscopy result.

Results: The pathological results were compared with 676 lymph nodes which were evaluated with SCM and 86 lymph nodes which were evaluated with ECM. Forty-nine true-positive, 136 true-negative, and 11 false-negative results were found in SCM and ECM. With these results, the sensitivity, specificity, negative predictive value, and accuracy for combined technique were calculated as 81.7%, 100%, 92.5% and 94.4%, respectively.

Conclusion: We recommend that SCM and ECM should be classified together under “mediastinoscopy” in the staging of NSCLC when other non-invasive procedures are unavailable.

Keywords : Mediastinoscopy; non-small cell lung cancer; staging
Viewed : 10269
Downloaded : 2348