ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
An evaluation of 6% hydroxyethyl starch 130/0.4 use in fluid therapy following coronary artery surgery
Ahmet Barış Durukan1, Hasan Alper Gürbüz1, Elif Durukan2, Nevriye Salman3, Murat Tavlaşoğlu4, Fatih Tanzer Serter1, Halil İbrahim Uçar1, Cem Yorgancıoğlu1
1Department of Cardiovascular Surgery, Medicana International Ankara Hospital, Ankara, Turkey
2Department of Public Health, Medicine Faculty of Başkent University, Ankara, Turkey
3Department of Anesthesiology and Reanimation, Medicana International Ankara Hospital, Ankara, Turkey
4Department of Cardiovascular Surgery, Diyarbakır Military Hospital, Diyarbakır, Turkey
DOI : 10.5606/tgkdc.dergisi.2013.7256
Background: This study aims to compare the effects of 6% hydroxyethylstarch 130/0.4 with a commonly used balanced electrolyte solution in patients undergoing coronary artery bypass surgery.

Methods: One hundred and fifty seven patients who underwent coronary artery bypass surgery were randomized into two groups. The first group received 6% hydroxyethyl starch 130/0.4, while the second group received a commonly used balanced electrolyte solution. The effects of both solutions on postoperative outcomes were studied.

Results: Six percent hydroxyethyl starch 130/0.4 did not increase postoperative blood loss and the amount of blood and blood products (p>0.05). No adverse effect was observed on renal and pulmonary functions. Intubation time, intensive care unit stay and postoperative duration of hospital stay did not differ between the groups (p>0.05). Hydroxyethyl starch had no effect on the occurrence of postoperative atrial fibrillation (p>0.05).

Conclusion: Six percent hyroxyethyl starch 130/0.4 may be considered safe in fluid therapy following coronary bypass surgery.

Keywords : Cardiac surgery; crystalloid solutions; hydroxyethyl starch
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