ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
An outcome comparison of adenocarcinoma of the esophagus to squamous cell carcinoma after transthoracic esophagectomy
Atilla Eroğlu1, Yener Aydın1, Ömer Yılmaz2, Ali Bilal Ulaş1
1Department of Thoracic Surgery, Medical Faculty of Atatürk University, Erzurum, Turkey
2Department of Gastroenterology, Medical Faculty of Atatürk University, Erzurum, Turkey
DOI : 10.5606/tgkdc.dergisi.2013.7209
Background: In this study, we assessed the results of adenocarcinoma (ADC) and squamous cell carcinoma (SCC) cases of distal esophagus, who underwent transthoracic esophagectomy.

Methods: Between January 1999 and July 2010, 22 ADC (12 females, 10 males; mean age 61.5±11.2 years; range 40 to 79 years) and 48 SCC cases of distal esophagus (28 females, 20 males; mean age 56.8±12.1 years; range 28 to 83 years), who underwent transthoracic esophagectomy were retrospectively analyzed.

Results: The most commonly encountered symptoms of ADC and SCC were dysphagia and weight loss (90.9%, 40.9% and 93.8%, 37.5%, respectively). Six cases (27.3%) with ADC and 18 cases with SCC (37.5%) had smoking history. Four cases with ADC (18.2%) and 21 cases with SCC (43.8%) developed postoperative complications (p=0.033). No intraoperative mortality is observed in ADC cases, while three SCC cases (6.3%) died intraoperatively. Median survival was 34.3 months in ADC and 30.5 months in SCC. Five-year survival was 33.3% in ADC and 17.1% in SCC cases (p=0.55).

Conclusion: In this study, it was observed that postoperative complication rate was significantly higher in SCC compared to patients with ADC; however, there was no statistically significant difference in the long-term survival. Transthoracic esophagectomy appears to be a safe treatment modality in distally located esophagus cancer cases.

Keywords : Esophageal cancer; histology; transthoracic esophagectomy
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