ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
The effect of coronary artery bypass grafting on aortic functions
Fahriye Vatansever Ağca1, Kemal Karaağaç1, Erhan Tenekecioğlu1, Özlem Arıcan Özlük1, Dursun Topal1, Burak Erdolu2, Şenol Yavuz2, Mustafa Yılmaz1
1Departments of Cardiology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey
2Departments of Cardiovascular Surgery, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey
DOI : 10.5606/tgkdc.dergisi.2015.9581
Background: This study aims to investigate the effect of coronary artery bypass grafting (CABG) on aortic functions.

Methods: Thirty-two consecutive patients (mean age 61.6±9.4 years) with multi-vessel coronary artery disease (CAD) who underwent CABG surgery with cardiopulmonary bypass by the same surgical team were included in this study. The severity of the disease was calculated by the Gensini score index. Aortic function indices such as aortic cross-sectional compliance, aortic distensibility, and aortic stiffness index were calculated by echocardiography preoperatively, and at third and six months postoperatively.

Results: Aortic functions of patients with severe or extensive CAD with high Gensini score (mean 98.3±38.1) improved at postoperative period. Aortic cross-sectional compliance increased from preoperative 2.62±1.5 cm2/mmHg to 3.52±1.6 cm2/mmHg at three months (p=0.21), and to 3.79±1.5 cm2/mmHg at six months (p<0.01) postoperatively. Increase in aortic distensibility was measured as 3.5±2.3 cm2/dyne x10-6, 4.6±2.5 cm2/dyne x10-6 (p=0.33), and 4.8±2.1 cm2/dyne x10-6 (p<0.01) preoperatively, and at three months and six months postoperatively, respectively. Aortic stiffness index decreased from 3.2±0.7 to 2.9±0.6 (p=0.20), and to 2.8±0.4 (p<0.01) preoperatively, at three months and at six months postoperatively, respectively.

Conclusion: Proper revascularization via on-pump CABG with aortic cross-clamp results in a significant improvement in aortic functions.

Keywords : Aortic stiffness; coronary artery disease; coronary bypass surgery
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