This study presents the case of a 56-year-old female patient suffering from repeated epileptic seizures. No abnormality was observed following cranial magnetic resonance imaging and electroencephalogram, and treatment with antiepileptic drugs had no obvious effects. Subsequently, an abnormal blood glucose level was observed during epileptic seizures. Severe hypoglycemia was highly suspected to be the cause of seizures. Absent respiration on the right middle and lower chest was observed through further physical examination. A thoracic computed tomography scan revealed a giant heterogamous mass in the patient’s right thoracic cavity. This massive tumor was completely resected, and blood glucose level returned to normal shortly after the excision of the tumor. Immunohistochemical staining of the resected mass confirmed it to be a solitary fibrous tumor of the pleura. The patient remained in a favorable condition and did not suffer the recurrence of epileptic seizures over a 12-month follow-up period. To our knowledge, this is the first report on a giant solitary fibrous tumor of the pleura complicated with epileptic seizures caused by severe tumor-induced hypoglycemia.

Keywords : Epileptic seizures; hypoglycemia; solitary fibrous tumor