Aneursyms of the sinus of Valsalva and the fistulas that result from their expansion and rupture into contiguous structures, are rare malformations. Infective endocarditis is one of the main reasons of acquired aneursyms. This report specifically seeks to describe our experience with surgical treatment of aneursyms of the sinus of Valsalva secondary to infective endocarditis in 6 patients operated on between December 1993 and April 1994. In these 6 operations, gluteraldehyde treated autologous pericardium was used as a patch. Additionally when the aortic side of the sinus of Valsalva was repaired, the patch was also sutured with seperate single pledget stitches to the annulus, so that the annulus was strengthened at the same time. Despite the limited experience we believe that autologous pericardial patch is superior to the Dacron patch. Thus the incidance of secondary infection is reduced by avoiding synthetic foreign material. Hospital mortality rate was 33%. The two survivors are folIowed up for 12 and 16 months and have an active life.