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Deep vein thrombosis in pregnant women with heterozygous factor-V Leiden mutation: a case report
Deep vein thrombosis in pregnant women with heterozygous factor-V Leiden mutation: a case report
İyad Fansa1, Arif Güngören2, Ali Ulvi Hakverdi2, Şahin Zeteroğlu2, Çağcıl Yetim2
1Department of Cardiovascular Surgery, Medicine Faculty of Mustafa Kemal University, Antakya
2Department of Obstetrics and Gynecology, Medicine Faculty of Mustafa Kemal University, Antakya
Deep vein thrombosis during pregnancy is an important risk
factor increasing maternal morbidity and mortality. Factor
V Leiden mutation is the most frequent one among many
hereditary and acquired thrombophilic risk factors during
pregnancy. In a 23-year-old woman who had been pregnant
for 11 weeks and applied to hospital with sudden onset pain,
swelling, and erythema in her left lower extremity, a thrombus
from left main iliac to superficial femoral veins was
detected via Doppler ultrasonography. She was hospitalized
and low molecular-weight heparin (enoxaprine sodium) was
initiated with a dosage of 12000 IU/day. She showed a rapid
healing clinically and was followed up with enoxaprine and
varsity sock until delivery. After labor, the dosage of enoxaprine
was halved and withdrawn after six weeks, and oral
warfarin sodium was started. The patient is still continued
to be followed up without any problems.
Keywords : Deep vein thrombosis; enoxaprine; factor V Leiden mutation; pregnancy
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