ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Effect of sex on early surgical outcomes of isolated coronary artery bypass grafting
Jamshid Bagheri1, Mahmoud Reza Sarzaeem1, Ali Kord Valeshabad2, 3, Amin Bagheri1, Mohammad Hussein Mandegar1
Cardiac Surgery and Transplantation Research Center (CTRC), Tehran University of Medical Sciences, Tehran, Iran
1Cardiac Surgery and Transplantation Research Center (CTRC), Tehran University of Medical Sciences, Tehran, Iran
2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA
3Farzan Clinical Research Institute, Tehran, Iran
DOI : 10.5606/tgkdc.dergisi.2014.8997
Background: In this study, we investigated possible effects of sex on early surgical outcomes of isolated coronary artery bypass grafting (CABG).

Methods: In this retrospective review of existing database including patients with heart disease, 1,390 consecutive cases (393 males, 997 females; mean age 58.7±10.1 years; range 23 to 87 years) who underwent isolated CABG in Shariati Hospital, Tehran Iran between August 2007 and March 2011 were recruited. Male and female sexes were compared for preoperative characteristics. A stepwise multivariate logistic regression analysis was performed to evaluate possible effects of sex on postoperative mortality and morbidity.

Results: Female patients were older with a higher prevalence of diabetes mellitus, hypertension, hypercholesterolemia and hyperlipidemia. The mortality rate was significantly higher in women compared to men (6.9% vs. 2.3%; p<0.001). Female sex was an independent predictor of postoperative mortality, septicemia, prolonged mechanical ventilation, leg infection, and renal complications.

Conclusion: Our study results show that female sex is an independent predictor of postoperative mortality and some of morbidities. Therefore, specific attention should be warranted to female patients undergoing isolated CABG.

Keywords : Coronary artery bypass grafting; morbidity; mortality; postoperative; sex
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