ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
TREATMENT AND PROGNOSIS IN PATIENTS WITH THYMOMA
, Tuba LİMAN, İrfan TAŞTEPE, Sedat DEMİRCAN, Salih TOPÇU, Güven ÇETİN, * Akın KUZUCU, * Ömer SOYSAL,** Haldun Şükrü ERKAL
Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Merkezi, Göğüs Cerrahi Kliniği, ANKARA
* İnönü Üniversitesi, Turgut Özal Tıp Merkezi, Göğüs Kalp Damar Cerrahisi Anabilim Dalı, MALATYA
** İnönü Üniversitesi, Turgut Özal Tıp Merkezi, Radyasyon Onkolojisi Anabilim Dalı, MALATYA
This report retrospectively documents the therapy in 32 patients with thymoma at Atatürk Chest Disease and Thoracic Surgery Center from 1987 to 1996. According to the initial Masoka staging of thymoma 7 patients were in stage I,4 in stage II, 16 in stage III, and 5 in stage IV. There were 10 patients with tumors with lymphocyle predominant histology, eight with epithelial predominant histology, eleven with mixed histology. Eleven patients underwent total resection, eight had subtotal resection and 13 had biopsy alone. Actuarial survival curves were constructed according to Kaplan-Meier method,comparison between survival curves was performed by two sided log-rank test. Five year survival was 86% for stage I, 75% for stage II, 27% for stage III, 27% for stage IV; 0% for patients with epithelial predominant histology, 76% for patients with mixed histology, 80% for patients with lymphocyte predominant histology, 80% for patients who had total resection, 31% for patients with subtotal resection and 21% for patients with biopsy alone. Differences in survival between the early stage versus late stage groups, complete resection versus incomplet resection or biopsy groups and patients with lymphocyte predominant and mixed thymomas versus epithelial thymomas were statistically significant.
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