Özet

In this article, we report a 37-year-old male case who underwent an emergency surgery of injured left atrium by transcatheteral closure of atrial septal defect (ASD). The patient underwent an urgent surgery when he developed tamponade during the transcatheteral closure of the secundum ASD at the coronary angiography laboratory. After median sternotomy, pericardium was opened. The exploration revealed ruptured left atrial roof and active bleeding at this region. One centimeter diameter ruptured left atrial ceiling was primarily closed by 4/0 prolene, followed by the primary closure of the secundum ASD. Postoperative period was uneventful and the patient was discharged on the fifth postoperative day.

Atrial septal defect (ASD) is the most common congenital heart disease seen in adults, and comprises 5-10% of all congenital heart diseases.[1-4] A great proportion of the patients are asymptomatic up to adulthood, but early diagnosis and treatment is crucial because of the complications seen in patients in their 30s and 40s, such as right heart failure, pulmonary hypertension, and arrhythmia, if left untreated.

Though surgical closure of the ASD is a preferred and a low-risk method of treatment, it also carries the risks of post-pericardiotomy syndrome, arrhythmia, pleuro-pericardial effusions, the need for blood transfusion during surgery and scar formation after healing.[5] In our era, transcatheter closure of the defect in secundum- type ASDs is a frequent method of treatment.[5,6] Though results after transcatheter closure resemble those after surgical closure, low mortality rates, scar-free healing, and low hospitalization time are reasons why transcatheter treatment is a good alternative to surgery.

Cardiac perforation is a rare complication seen during percutaneous closure, with an incidence ranging from 0.1-0.4% depending on the instruments used.[7,8] The mortality rate associated with this complication is very high.

A 37-year-old male patient was admitted to the cardiology outpatient department with dyspnea and palpitation. His physical examination revealed a grade 1/4 systolic murmur and a grade 2/4 systolic murmur in the tricuspid zone. His electrocardiogram was sinusal, but there was right bundle branch block. Transthoracic echocardiography (TTE) revealed an ostium secundum defect on the interatrial septum and a mild dilatation of the cardiac chambers. The patient’s pulmonary artery pressure was 40 mmHg. Transesophageal echocardiography (TEE) revealed the secundum-type ASD with a diameter of 31 mm. Percutaneous closure was planned.

The patient was admitted to the angiography unit, and the procedure was performed under general anesthesia with TEE support. A 34 mm Amplatzer (AGA Medical Corporation, Amplatzer Septal Occluder, USA) septal occluder (ASO) device was prepared to be used in the procedure. A 14F sheath was inserted through the right femoral vein, and a pig tail catheter was placed in the left upper pulmonary vein under scopy and TEE assistance. A long ASO loader was then inserted into the pulmonary vein through the pigtail, and the ASO was placed at the end of the loader, but it was not opened. At the same time, bradycardia developed, and in a short time, pericardial effusion was inspected. After observing cardiac tamponade, pericardiosynthesis was performed, and approximately 200 cc of hemorrhagic effusion was drained. The patient was then taken to emergency surgery.

A median sternotomy was performed under general anesthesia. After performing a pericardiotomy, 500 cc of blood was aspirated. A 1 cm bleeding lesion on the left atrial roof was observed. After aortobicaval cannulation and establishing cardiopulmonary bypass (CPB), a mild hypothermia was obtained (32-34 °C). The lesion was sutured primarily with 4/0 polypropylene sutures, and a cross-clamp was applied. Diastolic arrest was obtained by cold blood cardioplegia. A secundum-type ASD 35 mm in diameter was visualized after a right atriotomy (Figure 1). The ASD was then closed primarily with 3/0 polypropylene sutures. Next, the cross-clamp was removed after the incisions were sutured. With the termination of CPB and routine chest closure, the operation was completed. The patient was discharged on the fifth day after an postoperative period with no complications.

Figure 1: Secundum atrial septal defect closed after repairing the roof of the left atria.

Tartışma

Cardiac catheterization has been used in treatment as well as in diagnostic evaluation in the last three decades. Transcatheter ASD closure has been commonly used in the last few years as an alternative treatment to the customary surgical treatment.

Though major complications due to percutaneous closure are rare, they can cause severe clinical results. Perforation is the first of all major complications. Cardiac rupture might be seen because of this percutaneous closure technique and could be treated surgically in the hospitalization time. Although transcatheter closure of ASD has been remarkably successful, cardiac perforation could develope in term discharged from the hospital and it could be commonly fatal.[7]

The mechanism of the perforation is not clearly known. The round and flexible construction of Amplatzer septal occluders is designed to diminish the risk of perforation;[9] however the places the ASOs contact run the risk of deformation. Recent reports have underlined the fact that perforations are almost always adjacent to the device on the anterosuperior atrial and aortic walls because it is believed that these locations are sensitive to trauma.

Rupture due to a pigtail catheter, the balloon sizing procedure, and utilizing the device are the reasons for perforation in different case studies found in literature.[9,10] In our case, the reason for the perforation of the left atrium was probably the pigtail catheter or the long loader sheath.[10,11]

In conclusion, life-threatening complications can occur during percutaneous treatment, but emergency pericardiosynthesis before surgery can reduce mortality and morbidity. Even in the most experienced clinics, the cardiovascular surgery team should be waiting on standby to handle and manage any complications. Therefore, these procedures should preferably be carried out in hybrid operating rooms in order to be ready for any abnormal situation.

Declaration of conflicting interests
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Funding
The authors received no financial support for the research and/or authorship of this article.

Kaynaklar

1) Therrien J, Webb GD. Congenital heart disease in adults. In: Braunwald E, Zipes DP, Libby P, editors. Braunwald’s heart disease: a textbook of cardiovascular medicine. 6th ed. Philadelphia: W. B. Saunders; 2001. p. 1592-621.

2) Oto MA, Aytemir K, Ozkutlu S, Kaya EB, Kabakcı G, Ateş AH, et al. Percutaneous closure of interatrial septal defects: mid-term follow-up results. [Article in Turkish] Turk Kardiyol Dern Ars 2011;39:385-95. doi: 10.5543/tkda.2011.01474.

3) Yüce M, Ozer O, Cakıcı M, Sarı I, Davutoğlu V, Doğan A, et al. Closure of secundum atrial septal defects by the Amplatzer occluder device. [Article in Turkish] Turk Kardiyol Dern Ars 2011;39:35-40.

4) Erentuğ V, Bozbuğa N, Polat A, Kayalar N, Kırali K, İpek G,et al. Yaşlılarda sekundum atriyal septal defektin cerrahi tedavi sonuçları: Turk Gogus Kalp Dama 2005;13:210-4.

5) Du ZD, Hijazi ZM, Kleinman CS, Silverman NH, Larntz K; Amplatzer Investigators. Comparison between transcatheter and surgical closure of secundum atrial septal defect in children and adults: results of a multicenter nonrandomized trial. J Am Coll Cardiol 2002;39:1836-44.

6) Holzer R, Hijazi ZM. Interventional approach to congenital heart disease. Curr Opin Cardiol 2004;19:84-90.

7) Amin Z, Hijazi ZM, Bass JL, Cheatham JP, Hellenbrand WE, Kleinman CS. Erosion of Amplatzer septal occluder device after closure of secundum atrial septal defects: review of registry of complications and recommendations to minimize future risk. Catheter Cardiovasc Interv 2004;63:496-502.

8) Schräder R. Catheter closure of secundum ASD using “other” devices. J Interv Cardiol 2003;16:409-12.

9) Harper RW, Mottram PM, McGaw DJ. Closure of secundum atrial septal defects with the Amplatzer septal occluder device: techniques and problems. Catheter Cardiovasc Interv 2002;57:508-24.

10) Chessa M, Carminati M, Butera G, Bini RM, Drago M, Rosti L, et al. Early and late complications associated with transcatheter occlusion of secundum atrial septal defect. J Am Coll Cardiol 2002;39:1061-5.

11) Divekar A, Gaamangwe T, Shaikh N, Raabe M, Ducas J. Cardiac perforation after device closure of atrial septal defects with the Amplatzer septal occluder. J Am Coll Cardiol 2005;45:1213-8.