Methods: Seven patients (mean age 23.6±32.5 months; range 6 to 96 months and mean weight 9.6±4.6 kg; range 7 to 20 kg) who underwent operation with the diagnosis of d-transposition of great arteries (d-TGA) were included in the study. Simple TGA with atrial septal defect was observed in three of the seven patients and in the remain four patients complex TGA (ventricular septal defect and pulmonary stenosis) was present. Before Senning operation, four (57%) patients had undergone balloon atrial septostomy. Mean preoperative pulmonary arterial pressure was 34.6±27.5 mmHg. Mean preoperative systemic arterial oxygen saturation was 76.3±9.2 percent. Preoperatively, New York Heart Association (NYHA) functional class II was observed in six (86%) patients and class III in one (14%) patient. The retrospectively analyzed parameters included cardiopulmonary bypass time, aortic cross-clamp time, mechanical ventilation duration, and intensive care unit stay.
Results: One (14%) patient died in the hospital after the operation. Mean cardiopulmonary bypass time was 155.9±23.6 minutes and aortic cross-clamp time was 99.9±23.5 minutes. Postoperatively all patients remained in normal sinus rhythm, except for one patient who developed complete atrioventricular block and this patient required a permanent pacemaker. Mild superior vena cava baffle obstruction developed in one patient with a mean gradient of 2 mmHg. The mean follow-up was 20.4±18.3 months. Five (84%) patients were classified as class I according to the NYHA functional classification.
Conclusion: Senning procedure performed in patients with d-TGA during infancy period is a safe operation with low mortality and morbidity rates in the mid-term follow-up.