The Effect of Pulsatile Flow on Kidney Functions During Cardiopulmonary Bypass

Barbaros KINOĞLU, Halil TÜRKOĞLU, Tufan PAKER, Tayyar SARIOĞLU, Aydın AYTAÇ

İstanbul Üniversitesi Kardiloyoji Enstitüsü Kalp ve Damar Cerrahisi Anabilim Dalı, İstanbul

The effect of pulsatile and continous flow on kidney functions during cardiopulmonary bypass (CPB) was investigated. In 15 patients, continous flow perfusion, (Group I) and in 20 patients pulsatile flow perfusion (Group II) was performed for about an hour on CPB.
At the end of cortic cross clamping BUN, creatinin, urine osmolarity (Uosm), urine Na+ concentration (UNA+) and urine volume were measured. Later, 24 hour postoperatively creatinin clearance, free H2O clearance and urine osmolarity values were recorded and compared between the groups.
No statistically important difference was found (p>0.05).
Besides, in patients whom BUN and creatinin values were followed up to 7th postoperative day, we couldn't find any sign that made us think about kindeny dispunction.
So with these datas, we made a conclusion that in perfusion time that last about an hour, the pulsatile flow has no superiority to continous flow with respect to effects on kidney functions.

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