ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
The effects of perioperative ultrafiltration on postoperative outcomes in dialysis-dependent patients undergoing open heart surgery
İsa Coşkun1, Yücel Çölkesen2, Orhan Saim Demirtürk1, Hüseyin Ali Tünel1, Öner Gülcan1, Rıza Türköz1
1Department of Cardiovascular Surgery, Başkent University Adana Teaching and Medical Research Center, Adana, Turkey
2Department of Cardiology, Başkent University Adana Teaching and Medical Research Center, Adana, Turkey
DOI : 10.5606/tgkdc.dergisi.2013.7133
Background: This study aims to investigate the effects of perioperative ultrafiltration (UF) on postoperative outcome in hemodialysis-dependent patients undergoing open heart surgery.

Methods: Between March 2000 and May 2008, 46 hemodialysis-dependent patients who underwent open heart surgery were included. Patients were divided into two groups based on utilization of ultrafiltration: UF (+) and UF (-) group. All patients underwent hemodialysis one day before surgery and two days after surgery. Of 46 patients, 26 had UF during surgery (UF (+) group). The length of hospital stay including intensive care unit and morbidity and mortality rates were compared between the groups. Pre- and postoperative central venous pressure, blood urea nitrogen (BUN), creatinine, serum potassium, hemoglobin (Hgb) concentrations were analyzed.

Results: The length of intensive care unit stay (56±28 hours vs. 95±93 hours, respectively; p=0.04) and hospital stay (5.5±1.4 days vs. 8.1±3.4 days, respectively; p=0.002) were significantly different between the groups. There were significant differences in postoperative mean values of BUN (50.6±13.5 mg/dl vs. 59.8±13.7 mg/dl, respectively; p=0.02) and hemoglobin (9.9±1.0 g/dl vs. 8.8±0.9 g/dl, respectively; p=0.001) between the groups.

Conclusion: Utility of perioperative UF in dialysisdependent patients during open heart surgery may shorten the length of hospital stay and improve biochemical and hemodynamic parameters.

Keywords : Dialysis-dependent patient; open heart surgery; ultrafiltration
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