ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Effects of mean platelet volume on survival of the patients undergoing below-knee bypass
Kazım Beşirli1, Safa Göde1, Caner Arslan1, Berk Arapi1, Berra Zümrüt Tan1, Hayriye Ertem Vehid2, Kamil Hasan Tüzün1
1İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Kalp ve Damar Cerrahisi Anabilim Dalı, İstanbul, Türkiye
2İstanbul Üniversitesi Çocuk Sağlığı Enstütüsü, Aile Sağlığı Anabilim Dalı, İstanbul, Türkiye
DOI : 10.5606/tgkdc.dergisi.2013.7643
Background: This study aims to investigate the relationship of the mean platelet volume (MPV) values, risk factors, treatment protocols with the mortality in patients undergoing below-knee bypass.

Methods: A total of 117 patients (96 males, 21 females; mean age 60.6 years; range 45 to 84 years) who underwent belowknee bypass were enrolled in this study. Patients with one of the risk factors at least including diabetes mellitus, hypertension, hyperlipidemia, smoking and obesity were accepted as highrisk patients. After surgery, patients were divided into four groups according to the MPV values. These groups were compared with each other in terms of survival time. Age, the amount of cigarette smoking, platelet count, treatment protocol, sex and risk status parameters were statistically analyzed.

Results: There was no statistically significant difference in term of age (p=0.074), the amount of cigarette (p= 0.882) platelet count (p= 0.496), and treatment protocol (p=0.278) between survivors and ex-patient. No statistically significant difference was observed in terms of sex (p=0.303) and risk (p=0.550) parameters between the mortality groups. The second MPV group (7.5 fl≤MPV≤9.4 fl) had longer survival than third MPV group (9.5 fl≤MPV≤11.4 fl) patients (p<0.001, f=8.62). It was observed that patients with higher MPV value had longer survival than patients with lower MPV values due to the tendency for thrombosis.

Conclusion: Our study results suggest that high MPV values constitute an important risk factor for survival of patients with below-knee bypass. The MPV values in the routine hemogram appears to be a practical method providing important clues regarding the survival of these patients.

Keywords : Below-knee bypass; mean platelet volume; survival
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