ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Aspergillus endocarditis in a patient with acute lymphoblastic leukemia
Ali Rıza Karacı1, Buğra Harmandar1, Ahmet Şaşmazel1, Numan Ali Aydemir1, İlker Kemal Yücel2, Serap Şimşek3
1Department of Pediatric Cardiac Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey
2Department of Pediatric Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey
3Department of Infectious Diseases, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey
DOI : 10.5606/tgkdc.dergisi.2013.6801
Aspergillus endocarditis is a life-threatening condition. Establishment of the diagnosis and treatment remain highly challenging. Aspergillus endocarditis should be suspected in immunocompromised patients with negative blood cultures and vegetation on echocardiography. Definitive diagnosis is based on tissue histology and culture. The best treatment approach requires aggressive surgical debridement in combination with prolonged antifungal therapy. In this article, we report a 5.5-yearold boy with acute lymphoblastic leukemia in whom immunosuppression-related Aspergillus endocarditis developed. The patient underwent a Ross operation and excision of a large vegetation in the left ventricular outflow tract. However, he died due to possible intracerebral abscesses during follow-up.
Keywords : Aspergilloma; Aspergillus endocarditis; infective endocarditis; Ross procedure
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