ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Early period lung transplantation results of Yedikule Organ Transplantation Center: our three-year experience
Songül Büyükkale1, Necati Çıtak1, Özgür İşgörücü1, Cem Emrah Kalafat1, Yunus Aksoy1, Çağrı Cemaller1, Çiğdem Obuz1, Barış Açıkmeşe2, Ayşe Ulukol3, Nur Dilek Bakan2/sup>, Adalet Demir1, Adnan Sayar1
1Yedikule Göğüs Cerrahisi ve Göğüs Hastalıkları Eğitim ve Araştırma Hastanesi, Göğüs Cerrahisi Kliniği, İstanbul, Türkiye
2Yedikule Göğüs Cerrahisi ve Göğüs Hastalıkları Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, İstanbul, Türkiye
3Yedikule Göğüs Cerrahisi ve Göğüs Hastalıkları Eğitim ve Araştırma Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, İstanbul, Türkiye
DOI : 10.5606/tgkdc.dergisi.2017.12582
Background: This study aims to present the early period lung transplantation results of our lung transplantation center.

Methods: We retrospectively analyzed 31 lung transplantations (21 bilateral, 8 single-sided, and 2 retransplantations) performed on 29 patients (17 males, 12 females; mean age 41.4±11.7 years; range 19 to 59 years) in Yedikule Chest Diseases and Thoracic Surgery Hospital between March 2012 and February 2015.

Results: Of the patients, transplantation indications were bronchiectasis in nine, emphysema in eight, interstitial pulmonary disease in six, sarcoidosis in two, posttransplantation bronchial stenosis in two, and other lung diseases in four (alpha-1 antitrypsin deficiency, alveolar microlithiasis, destroyed lung due to tuberculosis, silicosis). Median waiting duration of patients in organ transplantation list was 6.3±4.8 months (range 1 to 9 month). Perioperative extracorporeal membrane oxygenation requirement rate was 45.1% (n=14). Ischemia time was 342±79 minutes for single lung transplantation and 535±85.9 minutes for bilateral lung transplantation. No perioperative mortality was observed. Early mortality rate was 25.8% (n=8). The only factor affecting early mortality was perioperative extracorporeal membrane oxygenation requirement (odds ratio=16, %95 confidence interval: 1.6-155, p=0.004). Ischemia time for both single and bilateral lung transplantations was longer in patients with early mortality; however, the difference was not statistically significant (p=0.318 and p=0.931, respectively). Of the patients, 18 are still alive who have been under follow-up since median 16.1±11.9 months (62%) (range 3 to 43 month). One-year overall survival rate was 59.2±9.6%, whereas one-year survival rate after exclusion of early mortalities was 78.2±9.6%.

Conclusion: Lung transplantation provides significant survival rates in selected patients.

Keywords : Early period results; end stage lung disease; lung transplantation; morbidity; mortality
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