ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Surgical treatment of pediatric thoracic Ewing tumors
Zerrin Özçelik1, Alper Avcı2, İsmail Can Karacaoğlu2, Banu İnce Durhan3, İlknur Banlı Cesur4, Cemal Özçelik2
1Department of Pediatric Surgery, Adana City Training and Research Hospital, Adana, Türkiye
2Department of Thoracic Surgery, Çukurova University Faculty of Medicine, Adana, Türkiye
3Department of Pediatric Hematology and Oncology, Adana City Training and Research Hospital, Adana, Türkiye
4Department of Pediatric Surgery, Adana City Training and Research Hospital, Adana, Türkiye
DOI : 10.5606/tgkdc.dergisi.2023.23269
Background: This study aims to determine the thoracic surgery techniques, surgical indications, the role and effectiveness of surgical treatment in multimodal treatment applied to pediatric Ewing sarcoma patients.

Methods: Between A pril 2 004 a nd N ovember 2 020, a t otal o f 1 5 p ediatric p atients ( 9 m ales, 6 f emales; mean age: 10.1±4.5 years; range, 3 to 18 years) who were diagnosed with primary thoracic Ewing sarcoma and operated were retrospectively analyzed. Tumor-related factors and treatment modalities for Ewing sarcoma originating from the chest wall and mediastinum were examined.

Results: The most common complaint was pain in nine patients. While the tumor originated from the ribs in nine patients, it originated from the soft tissue (n=2), mediastinum (n=2), and extra-thoracic tissue (n=2) in six patients. Complete resection was achieved in 10 patients. While neoadjuvant chemotherapy was applied to eight patients, chemotherapy and radiotherapy was applied to 14 and five patients, respectively. Bone marrow transplantation was performed in one patient. The mean follow-up was 54.2±44.9 months. Recurrence was seen in six patients in a mean duration of 17.8±7.4 months.

Conclusion: The most effective treatment for thoracic Ewing sarcoma is complete resection. Multimodal therapy in the form of surgical resection, chemotherapy and/or radiotherapy provides optimal efficacy and the most favorable survival. The follow-up period should be kept short, since recurrences are common.

Keywords : Ewing sarcoma, local treatment, recurrence, surgery
Viewed : 1252
Downloaded : 503