ISSN : 1301-5680
e-ISSN : 2149-8156
Turkish Journal of Thoracic and Cardiovascular Surgery     
Prognostic value of CHA2DS2-VASc score for the long-term cardiovascular events after coronary artery bypass grafting
Abdulkadir Ercan1, Orcun Gurbuz1, Zekeriya Afsin Culhaoglu2, Gencehan Kumtepe3, Hakan Ozkan4, Ahmet Yuksel5, Serdar Ener6
1Department of Cardiovascular Surgery, Istinye University Faculty of Medicine, Istanbul, Türkiye
2Department of Cardiology, Istinye University Faculty of Medicine, Istanbul, Türkiye
3Department of Cardiovascular Surgery, Meddem Hospital, Isparta, Türkiye
4Department of Cardiology, Medicana Bursa Hospital, Bursa, Türkiye
5Department of Cardiovascular Surgery, Bursa University Faculty of Medicine, Bursa, Türkiye
6Department of Cardiovascular Surgery, Medicana Bursa Hospital, Bursa Türkiye Received: March 26, 202
DOI : 10.5606/tgkdc.dergisi.2023.24964.
Background: This study aims to investigate the value of the CHA2DS2-VASc score in predicting long-term major cardiovascular events following coronary artery bypass grafting.

Methods: Between January 2008 and January 2010, a total of 559 patients (445 males, 114 females; mean age: 62.7±9.1 years; range, 35 to 84 years) who underwent elective coronary artery bypass grafting were retrospectively analyzed. At a mean of 10.7±3.1-year follow-up, major cardiovascular events were considered as the primary endpoint.

Results: The multivariate Cox hazard analysis identified the CHA2DS2-VASc score as an independent predictor of major cardiovascular events (hazard ratio: 1.615; 95% confidence interval: 1.038-2.511; p=0.034). The receiver operating characteristic curve analyses revealed that 3.5 was the most optimal cut-off value of the score predicting major cardiovascular events and the patients were divided into two groups accordingly. The Kaplan-Meier analysis demonstrated a significantly higher incidence of major cardiovascular events in proportion to a higher CHA2DS2-VASc score (p<0.001).

Conclusion: CHA2DS2-VASc score ?4, which includes many risk factors for cardiovascular events, can be used as an independent predictor of long-term major cardiovascular events after coronary artery bypass grafting.

Keywords : CHA2DS2-VASc score, coronary artery bypass grafting, coronary artery disease, major cardiovascular event
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